Cast & creator
Lizzy Caplan
Best known for Watch What Happens Live with Andy Cohen, The Tonight Show Starring Jimmy Fallon, The Simpsons
Elizabeth Anne Caplan (born June 30, 1982) is an American actress. Her performances as Virginia E. Johnson in the Showtime series Masters of Sex (2013–2016) and as Libby Epstein in FX on Hulu's Fleishman Is in Trouble (2022) have earned her nominations at the Primetime Emmy Awards. Her first acting role was on the television series Freaks and Geeks (1999–2000). Since then, she had series-regular roles in several television series including Related (2005–2006), Party Down (2009–2010; 2023), Das Boot (2018), Castle Rock (2019), Truth Be Told (2019), Fatal Attraction (2023), and Zero Day (2025). Caplan's film breakthrough came with her role as Janis Ian in Mean Girls (2004). Her other film appearances include My Best Friend's Girl (2008) Cloverfield (2008), Hot Tub Time Machine, 127 Hours (both 2010), Save the Date, Bachelorette (both 2012), The Interview (2014), Now You See Me 2, Allied (both 2016), and Cobweb (2023). Description above from the Wikipedia article Lizzy Caplan, licensed under CC-BY-SA, full list of contributors on Wikipedia.
Also known as: Elizabeth Caplan, Elizabeth Anne Caplan
37
film credits
44
television credits
79
1989–2027 · acting roles
6.5
average across scored titles
Signature credits
Known for
Across film & television
Filmography (81)
Showing 81 of 81 credits
Watch What Happens Live with Andy Cohen
Self - Guest
2009
The Tonight Show Starring Jimmy Fallon
Self
2014
The Simpsons
Virginia Johnson (voice)
1989
Late Night with Seth Meyers
Self - Guest
2014
Family Guy
Woman Arguing With Quagmire (voice)
1999
American Dad!
Debbie (voice)
2005
Conan
Self
2010
The View
Self
1997
Jimmy Kimmel Live!
Self
2003Jimmy Kimmel Live!
Self - Guest
2003
Smallville
Tina Greer
2001
New Girl
Julia Cleary
2011
True Blood
Amy
2008
The Last Leg
Self
2013
Childrens Hospital
Casey Klein
2008Childrens Hospital
Harmony
2008
Close Up with The Hollywood Reporter
Self
2015
The League
Rebecca Ruxin
2009
Comedy Bang! Bang!
Self
2012
Masters of Sex
Virginia Johnson
2013
Off Camera with Sam Jones
Self
2014
Chelsea
Self
2016
The Cleveland Show
2009
Angie Tribeca
Deirdre
2016
Mean Girls
Janis Ian
2004
Now You See Me: Now You Don't
Lula
2025
Party Down
Casey Klein
2009
Truth Be Told
Lanie Buhrman / Josie Buhrman
2019
Tru Calling
Avery Bishop
2003
Freaks and Geeks
Sara
1999
Castle Rock
Annie Wilkes
2018
Once and Again
1999
Inside Job
Reagan Ridley (voice)
2021
Now You See Me 2
Lula
2016
Das Boot
Carla Monroe
2018
The Interview
Agent Lacey
2014
Zero Day
Alexandra Mullen
2025
127 Hours
Sonja Ralston
2010
Undeclared
Beautiful Girl
2001
Fatal Attraction
Alex Forrest
2023
Fleishman Is in Trouble
Libby Epstein
2022
Allied
Bridget Vatan
2016
Cloverfield
Marlena
2008
Related
Marjee Sorelli
2005
The Class
Kat Warbler
2006
The Disaster Artist
Lizzy Caplan
2017
Mr. Sunshine
Vivian Cornelli
2011
Hot Tub Time Machine
April
2010
Cobweb
Carol
2023
Crossing Over
Marla
2009
The Night Before
Diana
2015
Orange County
Party Girl
2002
My Best Friend's Girl
Ami
2008The Pitts
Faith Pitt
2003
Extinction
Alice
2018
The People We Hate at the Wedding
Marissa
2022
Marvel One-Shot: Item 47
Claire Wise
2012
Bachelorette
Gena Myers
2012
Far Cry
The Boys from Brazil
Hannah Liebermann
Ill Behaviour
Nadia
2017Darkwing Duck
Gosalyn Mallard (voice)
The Last Rites of Ransom Pride
Juliette Flowers
2010
Save the Date
Sarah
2012
Crashing
Jacqueline
2007
3, 2, 1... Frankie Go Boom
Lassie
2012
The Sidekick
Bailey
2013
Home for Actresses
Lizzy
2011
Love Is the Drug
Sara Weller
2006From Where I Sit
Lily
2000
Drag
2027Drag
Executive Producer
2027
Beef
Audrey
2014
The Toll Road
Emily
2019
7 Up & Me
Self
2019
Everybody's Doing It
Angela
2002
Queens of Country
Jolene Gillis
2012
Successful Alcoholics
Lindsay
2010Successful Alcoholics
Producer
2010
High Road
Sheila
2012
Hardcore Action News
Lizzy Lyons
2003