The Blood Sisters

Erika, a club dancer, works hard day and night in hopes of accumulating enough money for her son Jolo's hospital bills. When a big opportunity finally knocks at her door, Erika is compelled to go the extra mile. She, however, finds herself entangled in a crime. Wanting to ensure Jolo's safety, Erika decides to leave him under the care of her longtime friend Bruce. Soon after, Erika sets out to clear her name.

Erika escapes to Manila to look for the killer, known only as “Ana” as her only lead. She seeks help from her childhood bestfriend Tonyo. The assassins find her but she is able to escape when the assassins shoot Carrie, a woman who looks exactly like Erika, and take her away. Earlier, Carrie Almeda just arrives from Sweden, but takes a detour to the mall to avoid the traffic. Later when her driver spots her, he does not notice the difference and takes her to her parents’ home in Santa Rosa, Laguna. Her parents also believe she is Carrie, but they are confused with her overall look, a drastic difference from the sophisticated Carrie they know. Erika decides to assume Carrie’s identity for the time being.

The Almedas welcome Erika home, thinking that she is Carrie. At her welcome party, Erika learns Carrie is getting married in two weeks to Samuel Hechanova, a popular pediatrician. As she browses through Carrie’ home videos, she sees how much loved Carrie is by her parents. She is intrigued with any possible connection to Carrie and asks her mother if she has a twin. Her mother Deborah is puzzled and notices something different about her daughter. In spite of her guilt, Erika tries her best to assume Carrie’s identity. She is shocked when she learns Carrie is an obstetrician, and that Carrie’s family owns the country’s largest medical facility specializing in infertility. Elsewhere in Benguet, Carrie and Erika have another lookalike, Agatha, who is getting ready to see her mother returning from abroad after a long stint as an OFW. Msanwhile, in a secluded location and heavily guarded by the syndicate lies the real Carrie, alive but in a coma. Her captors are caring for her, waiting for her to tell them where the ledger is.

Pretending to be Dr. Carrie is tough for Erika. She manages to get out of performing a cesarean section but doesn’t think she can continue with the charade much longer, she barely finished high school. Meanwhile, without giving herself away, she subtly asks her father if she has a twin. Her question reminds Norman of a secret he is keeping and brings him back to that fateful day he abducted Carrie from Adele. The Almedas have been searching for Adele after their surrogacy agreement fell through 8 months ago. They finally track her down in Davao. As Norman and his men fan the city to locate her, Norman reaches Adele at her home and takes Carrie, while Norman’s men snatch Erika from her grandmother in the wet market nearby. Unaware that Adele has triplets, Norman informs his men that he already has the child. Thinking they made a mistake, his men abandon Erika in an empty carton in the garbage dump. Meanwhile, Norman brings the infant home to a joyous Debbie. Elsewhere in Baguio, Agatha is not looking forward to meeting her mother who has been working abroad for the past 20 years. Adele is anxious about her relationship with Agatha.

The truth is that 21 years ago, Debbie and Norman Almeda hired their housekeeper Adele to serve as surrogate mother to carry their fertilized eggs in her womb. What originally started as a Surrogacy Agreement falls through when Adele suffers a miscarriage. With no viable fertilized eggs left and desperate for a child, Norman is aware that Adele is in love with him, so he seduces her and gets her pregnant again. They continue the charade while Debbie still believes Adele is carrying her biological child, unaware of the miscarriage. Adele suffers a change of heart when she realizes she cannot give up her own child. She escapes to Davao and delivers to girl triplets. Meanwhile, Norman hires men to get their child back as he searches himself. Unaware that he has triplets, Norman tracks Adele to her home and takes the infant from her. Adele’s mother arrives shortly after, distraught over Erika’s kidnap. By a cruel twist of fate, Adele loses two of her triplets that day. 21 years later, in Benguet, Agatha is tired of her comfortable life and plans to leave for Manila. She is angry at her mother for spending most of her growing up years working abroad and is not ready to have her at this time. Meanwhile, Adele is anxious about their relationship, seriously contemplating quitting her job in Dubai and staying for good so she can spend more time with Agatha. Elsewhere in Tanay, Carrie wakes up from her coma and seeing no one, reads her own medical chart. She is, after all, a physician.

Following Tonyo's advice, Erika decides to break off her engagement with Samuel. Samuel, however, opposes her decision and convinces her to postpone their wedding instead. This, in turn, causes the Bermudezes to fear losing their business ties with the Hechanovas. Soon after, Erika tries to sneak away from Carrie's mansion. Meanwhile, Carrie finally regains consciousness.

Erika gets into another altercation with Deborah over her refusal to marry Samuel. Unused to fighting with her daughter, Deborah finds herself distressed by Erika's blatant disobedience. Meanwhile, Carrie (Erich Gonzales) manages to escape from Greg’s henchmen. On her way home, she gets into a curious encounter with a woman who just looks exactly like her. She then tries to find out her true connection with the mysterious lady.

After confirming her relationship with Erika, Carrie becomes puzzled about her true identity. She corners Deborah and demands that she reveal the truth about her birth. This prompts Deborah to confess her long-kept secret to her daughter. Meanwhile, Erika learns that Anna Cruz, the woman who stole Greg’s (Ian de Leon) ledger, was found dead. Elsewhere, Agatha (Erich Gonzales) finally vents her resentments toward Adele (Cherry Pie Picache).

Erika is surprised to learn when her real birthday is. Having lived a luxurious life, Carrie feels sorry for her twin, who grew up without a family. She decides to prepare a birthday surprise for Erika. While the Almedas are setting up a grand party for Carrie, Rosemarie pays a visit to her “farm.” Elsewhere, Agatha continues to work hard to be able to leave Adele soon.

Tonyo brings Erika , Jolo, and Bruce to a special place to celebrate her birthday. Unbeknownst to them, Carrie asks Tonyo's help to give her twin sister a birthday surprise. Later, Erika experiences one of the happiest days of her life. Her celebration, however, is cut short by a sudden turn of events. Meanwhile, Adele throws a surprise birthday party for Agatha.

Unable to keep up impersonating her twin sister, Erika (Erich Gonzales) begs to swap places with Carrie (Erich Gonzales). Unfortunately, Andrea (Maika Rivera) overhears their conversation and immediately informs Rosemarie (Tessie Tomas) about it. Samuel (Enchong Dee), on the other hand, becomes confused by Carrie's erratic changes in her behavior. Soon, Rosemarie and Debbie (Dina Bonnevie) get the shock of their lives upon discovering Carrie's secret. Meanwhile, Agatha (Erich Gonzales) continues to give Adele (Cherry Pie Picache) the cold shoulder despite the latter's efforts to gain her affection.

The Almedas confirm that Erika (Erich Gonzales) is Carrie’s (Erich Gonzales) twin sister. Soon after, Erika has an emotional reunion with her real family. Rosemarie (Tessie Tomas), however, remains doubtful of her long-lost granddaughter. Unwilling to welcome Erika to her family, Rosemarie orders Andrea (Maika Rivera) to dig into Erika’s past. Meanwhile, Agatha (Erich Gonzales) becomes suspicious of her own identity.

The Almedas confirm that Erika (Erich Gonzales) is Carrie’s (Erich Gonzales) twin sister. Soon after, Erika has an emotional reunion with her real family. Rosemarie (Tessie Tomas), however, remains doubtful of her long-lost granddaughter. Unwilling to welcome Erika to her family, Rosemarie orders Andrea (Maika Rivera) to dig into Erika’s past. Meanwhile, Agatha (Erich Gonzales) becomes suspicious of her own identity.

Erika (Erich Gonzales), her son, and her friends receive a warm welcome from the Almedas. However, she becomes uncomfortable when Rosemarie (Tessie Tomas) probes about her past. Not long after, Carrie (Erich Gonzales) introduces her sister to Samuel (Enchong Dee). Meanwhile, Adele (Cherry Pie Picache) learns of Agatha’s (Erich Gonzales) fervent desire to break free from her. Elsewhere, Fabian (Dante Rivero) challenges Rainier (AJ Muhlach) and Juancho (Sandino Martin) to prove their worth to him.

Adele (Cherry Pie Picache) despairs at the thought of eventually losing Agatha (Erich Gonzales). Filled with guilt, Ligaya (Ruby Ruiz) accepts the blame for what Agatha has become and promises to help Adele make up for her shortcomings. Unbeknownst to them, Agatha enlists Dante's (Thou Reyes) help to fulfill her plan to start a new life. A sudden turn of events, however, causes Agatha to grow even more hateful of her mother. Later, an unlikely confession shakes Agatha's world.

Fabian faces a threat when Maria, one of the surrogate mothers, tries to sneak out of Paraiso. He then enlists the Bermudezes' help to prevent a big loss on his business. Desperate to save Maria's unborn child, Rosemarie compels Debbie to perform a risky operation that would endanger Maria. This then causes Debbie to become suspicious of Fabian's business. Meanwhile, Erika learns that the man who is after her is a powerful person. Unbeknownst to her, Juancho and Rainier race against each other to obtain information about her. Elsewhere, Agatha finally arrives in Manila.

A perplexing enigma leaves Debbie in shock after an unforeseen circumstance befell Maria. This then forces Debbie to think deeply about Fabian's possible involvement in the incident. Meanwhile, Adele goes to great lengths to find Agatha. Agatha, on the other hand, prepares for her next big step now that her desire to meet her biological family is within her grasp. At the Almedas' mansion, a pleasant surprise awaits Erika.

With her dreams finally turning into reality, Erika is grateful than ever to her twin sister, Carrie. Blessings continue to pour in for Erika as the Almedas officially welcome her to the family's medical business. Though hesitant, Erika gladly accepts the challenges bestowed upon her. Meanwhile, armed with her desire to win back Agatha, Adele finally decides to go to Manila. Upon learning of Adele's plan, Agatha immediately devises a scheme to get away from her estranged mother.

Agatha shows her appreciation for her friends. Erika is with her whole family during her baptism. As Erika and her family leave the chapel, a black van approaches them. The people in the black van were Fabian's goons who came to kidnap Erika. Rosemarie pleads with Fabian to let Erika go. Fabian is convinced by her plead and lets Erika go.

Debbie calls the police to conduct an investigation on who managed the kidnapping situation. Erika becomes anxious about the investigation about her case. As Carrie is headed to work, she catches a glimpse of who she thought was "Erika", but who was actually Agatha. The police, who are in charge of Erika's case, finds a house where Sancho de Leon lives.